WIP pS488 Antibody, anti-human, APC, REAfinity™

01MT04685

Clone REA537 recognizes the human Wiskott-Aldrich syndrome protein-interacting protein (WIP) antigen phosphorylated at serine 488 (pS488). WIP is a multifunctional adaptor implicated in a wide range of cellular functions, including cell adhesion, migration and chemotaxis, T cell activation and proliferation, and intracellular pathogen motility. WIP functions through binding to both globular and filamentous actin and several regulators of actin dynamics. WIP can also bind to and regulate the function of the actin-nucleation-promoting factor cortactin. In cells of haematopoietic origin, WIP is a