TrkA Antibody, anti-human, PE, REAfinity™

01MT11267

Clone REA430 recognizes the human TrkA antigen, a single-pass type I membrane protein which is also known as neurotrophic tyrosine kinase receptor type 1 (NTRK1). TrkA is a member of the neurotrophic tyrosine kinase receptor family and is involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation, and survival of sympathetic and nervous neurons. TrkA is the high affinity catalytic receptor for the nerve growth factor (NGF). As such, it mediates the multiple effects of NGF, which include neuronal differentiat