TGF-β RII Antibody, anti-human, Vio® Bright R720, REAfinity™

01MT08761

Clone REA903 recognizes the human transforming growth receptor beta 2 (TGF-β RII) antigen, a single-pass transmembrane protein belonging to the superfamily of serine/threonine kinase receptors. Members of this family bind different TGF-β cytokines (TGF-β1, TGF-β2, TGF-β3) and other growth factors and cytokine signaling proteins. The association between TGF-β RII and TGF-β2 phosphorylates proteins, that regulate the transcription of a subset of genes related to cell proliferation in the nucleus.Additional information: Clone REA903 displays negligible binding to Fc receptors.