TCR Vβ8 Antibody, anti-human, APC, REAfinity™

01MT13843

Clone REA1330 recognizes the human variable beta 8 subunit of the αβ T cell receptor (TCR Vβ8), expressed on a subset of T cells. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ8 is a variant of the TCR β chain. αβ T cells express a diverse αβ TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. For example, the TCR can directly bind to peptide fragm