TCR Vβ5 Antibody, anti-human, Vio® Bright B515, REAfinity™

01MT08733

Clone REA910 recognizes the human variable β 5 subunit of the αβ T cell receptor (TCR Vβ5). The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5 is a variant of the TCR β chain. αβ T cells express a diverse αβ TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. For example, the TCR can directly bind to peptide fragments, riboflavin precursors, and lipid