TCR Vβ12 Antibody, anti-mouse, Vio® Bright B515, REAfinity™

01MT09132

Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vβ12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vβ12 on mouse