TCF7 (TCF-1) Antibody, anti-human, PE, REAfinity™

01MT13930

Clone REA1422 recognizes the transcription factor TCF7 (TCF-1), a member of the lymphoid enhancer binding factor family of transcription factors with 16 isoforms. TCF7 (TCF-1) is involved in T-cell lymphocyte differentiation, in natural killer cell and innate lymphoid cell development. TCF7 (TCF-1) is down-regulated when CD34+ cells change into CD34- cells. The intact form of TCF7 (TCF-1) is essential for the survival of CD4+ CD8+ immature thymocytes. In resting cells TCF7 (TCF-1) functions as a transcriptional repressor.