STAT6 pY641 Antibody, anti-mouse, PE, REAfinity™

01MT13925

Clone REA390 recognizes the mouse signal transducer and activator of transcription 6 (STAT6) antigen phosphorylated at tyrosine 641 (pY641). STAT proteins transmit signals from a receptor complex to the nucleus and activate gene expression. The seven members of the STAT family are predominantly activated by growth factors and cytokines. STAT6 expression is found in many tissues. It is activated by two cytokines, IL-4 and IL-13, and plays a predominant role in the immune system. Once these cytokines bind to their cognate receptors, the associated Janus kinases (JAKs) are activated and phosphory