STAT6 Antibody, anti-human/mouse/rat, PE, REAfinity™

01MT02391

Clone REA210 recognizes the human signal transducer and activator of transcription 6 (STAT6) antigen, regardless of phosphorylation status. STAT proteins transmit signals from a receptor complex to the nucleus and activate gene expression. The seven members of the STAT family are predominantly activated by growth factors and cytokines. STAT6 expression is found in many human tissues. It is activated by two cytokines, interleukin 4 (IL-4) and IL-13, and plays a predominant role in the immune system. Once these cytokines bind to their cognate receptors, the associated Janus Kinases (Jak) are act