Sall4 Antibody, anti-human, PE, REAfinity™

01MT14014

Clone REA1462 recognizes the zinc finger transcription factor Sall4, that plays an essential role in the maintenance and self-renewal of embryonic stem cells and hematopoietic stem cells. In most adult tissues, SALL4 is not expressed or only expressed at a low level, except germ cells and hematopoietic stem cells. SALL4 can be reactivated in malignant tumors, including acute myeloid leukemia (AML), B-cell ALL (B-ALL), germ cell tumors, gastric carcinomas, bronchial carcinomas, breast carcinomas, hepatocellular carcinomas (HCC) and gliomas. Mutations of the SALL4 gene are associated with Okihir