S6 pS240 Antibody, anti-human, Vio® B515, REAfinity™

01MT03329

Clone REA420 recognizes the human 40S ribosomal protein S6 antigen phosphorylated at serine 240 (pS240). Ribosomal protein S6 is one of 33 proteins that comprise the 40 S ribosomal subunit and becomes phosphorylated at several serine residues upon mitogen stimulation. It plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Activation of the p90 ribosomal S6 kinases (RSKs) by serum, growth factors, tumor promoting phorbol esters, and oncogenic Ras is required for ribosomal protein S6 phosphorylation downstream of t