Progesterone Receptor Antibody, anti-human, PE, REAfinity™

01MT13865

Clone REA1386 recognizes the human Progesterone Receptor (PGR), a protein activated by the steroid hormone progesterone. It is expressed as two isoforms, PRA and PRB, which function as ligand-activated transcription factors or as repressors, depending on the isoform. In human endometrium, PRA and PRB are co-expressed in target cells. PGR plays a role in the regulation of eukaryotic gene expression and cellular proliferation and differentiation in target tissues.