PepTivator® Uveal Melanoma GNAQ_Q209L - premium grade, human

02MT00300

PepTivator Uveal Melanoma GNAQ_Q209L is a pool of lyophilized peptides, consisting of 15-mer, 10-mer, and 9-mer sequences containing the Q209L mutation of human Guanine nucleotide-binding protein subunit alpha-q (UniProt ID: P50148). Q209L is an important driver mutation that occurs with high frequency in Uveal melanoma.PepTivator Uveal Melanoma GNAQ_Q209L covers the mutated protein domain [DLQSVIFRMVDVGGLRSERRKWIHCFENV] and contains every 15-mer, 10-mer, and 9-mer peptide bearing the mutated amino acid. This diversity allows loading of HLA without prior knowledge of alleles.PepTivator Uveal M