PepTivator® RAS Q61K, premium grade

02MT00314

PepTivator RAS Q61K is a pool of lyophilized peptides, consisting of 15-mer, 10-mer and 9-mer sequences and containing the Q61K mutation. Q61K is a common driver mutation that occurs with high frequency across various human cancer types.PepTivator RAS Q61K covers the mutated protein domain RAS47-75 [DGETCLLDILDTAGKEEYSAMRDQYMRTG] and contains every 15-mer, 10-mer and 9-mer peptide bearing the mutated amino acid. This diversity allows loading of HLA without prior knowledge of alleles. The proteins H-Ras, N-Ras, and K-Ras share 90% identity in their G domain (residues 1–166), and this peptide p