PepTivator® RAS G12V, premium grade

02MT00287

PepTivator® RAS G12V is a pool of lyophilized peptides, consisting of 15-mer, 10-mer, and 9-mer sequences containing the G12V mutation. G12V is a common driver mutation that occurs with high frequency across various human cancer types.PepTivator RAS G12V covers the mutated protein domain [MTEYKLVVVGAVGVGKSALTIQLIQN] and contains every 15-mer, 10-mer, and 9-mer peptide bearing the mutated amino acid. This diversity allows loading of HLA without prior knowledge of alleles. The proteins H-Ras, N-Ras, and K-Ras share 90% identity in their G domain (residues 1–166), and this peptide pool covers the