PepTivator® RAS G12D, premium grade

02MT00291

PepTivator® RAS G12D is a pool of lyophilized peptides, consisting of 15-mer, 10-mer, and 9-mer sequences containing the G12D mutation. G12D is a common driver mutation that occurs with high frequency across various human cancer types. PepTivator RAS G12D covers the mutated protein domain [MTEYKLVVVGADGVGKSALTIQLIQN] and contains every 15-mer, 10-mer, and 9-mer peptide bearing the mutated amino acid. This diversity allows loading of HLA without prior knowledge of alleles. The proteins H-Ras, N-Ras, and K-Ras share 90% identity in their G domain (residues 1–166), and this peptide pool covers th