PepTivator® RAS G12C, premium grade

02MT00285

PepTivator® RAS G12C is a pool of lyophilized peptides, consisting of 15-mer, 10-mer and 9-mer sequences containing the G12C mutation. G12C is a common driver mutation that occurs with high frequency across various human cancer types.PepTivator RAS G12C covers the mutated protein domain [MTEYKLVVVGACGVGKSALTIQLIQN] and contains every 15-mer, 10-mer, and 9-mer peptide bearing the mutated amino acid. This diversity allows loading of HLA without prior knowledge of alleles. The proteins H-Ras, N-Ras, and K-Ras share 90% identity in their G domain (residues 1–166), and this peptide pool covers the