PepTivator® FMC63scFv (CD19) CAR Immunogenicity - research grade, human

02MT00006

PepTivator® FMC63scFv (CD19) CAR Immunogenicity is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids (aa) overlap, covering the complete FMC63 scFV protein from GenBank No. QHQ73567.1. Additionally, the 4GS linker sequence was replaced by the Whitlow linker (see also Background information).In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells.