Pan-Cytokeratin Antibody, anti-mouse, PE, REAfinity™

01MT14042

Clone REA1463 recognizes cytokeratin 4, 5, 6, 8, 10, 13 and 18 Cytokeratins, which are found in almost all epithelial cells, are polypeptides with keratin-containing intermediate filaments, which ensure form stability and cohesiveness. Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. Cytokeratin 6 is located in proliferating squamous epithelium, whereas Cytokeratin 5 is found in the basal, the intermediate and the superficial cell layers of stratified and transiti