p16 Antibody, anti-human, Vio® B515, REAfinity™

01MT09573

Clone REA973 recognizes the human p16 protein, a member of the cyclin-dependent kinases (CDKs), also known as cyclin-dependent kinase 4 inhibitor (CDKN2) or INK4A. p16 is a multiple tumor-suppressor protein that functions as a negative regulator of the proliferation of normal cells and tumorigenesis by forming heterodimers with CDK4 and CDK6. p16 is found in most of different cell types but it is not detected in brain or skeletal muscle.Additional information: Clone REA973 displays negligible binding to Fc receptors