p120 Catenin Antibody, anti-human, PE, REAfinity™

01MT13965

Clone REA1417 recognizes the human p120 Catenin antigen. p120 Catenin exists as four isoforms that range in size from 90 to 115 kDa. Expression of these isoforms is heterogeneous in human carcinomas, suggesting that altered expression contributes to malignancy. p120 Catenin is a prototypic member of subfamily of Armadillo-domain (ARM) proteins. The p120 ARM domain displays 22% homology to other ARM-domain proteins such as β-catenin and plakoglobin, which are basically cadherin binding proteins, suggesting the involvement of p120 in binding to cadherin. p120 associates with most classical (type