ORN R-2336

99MT00175

TLR7 and TLR8 are members of the Toll-like-receptor (TLR) family, recognizing (virally derived) double- or single-stranded RNA, leading to activation of immune cells. ORN R-2336 specifically activates human and murine TLR7 and induces a TLR7-biased spectrum of cytokines from human PBMCs (predominantly IFN-a).6