Nuclear Pore Complex Antibody, anti-human/mouse, PE, REAfinity™

01MT13608

Clone REA1353 recognizes the Nuclear Pore Complex Proteins (NPCs). NPCs form channels through the nuclear envelope that allow the passage of macromolecules between the cell nucleus and cytoplasm. The nuclear pore complex is a very complex network with a 110 megadalton (MDa) structure consisting of at least 500 protein subunits and has several functions such as regulating the transport of RNA, proteins and ribosome subunits. The proteins that make up the nuclear pore complex are known as nucleoporins. Several diseases are associated with pathologies of nucleoporins, including diabetes, Parkinso