NKX3.1 Antibody, anti-human, PE, REAfinity™

01MT13920

Clone REA1421 recognizes the human prostate-specific NKX3.1, an androgen-regulated homeodomain transcription factor, that is involved in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. NKX3.1 also functions as a tumor suppressor that controls prostate carcinogenesis. The expression of NKX3.1 protein is mostly decreased in primary prostate cancer.