mTOR (phospho S2448) Antibody, anti-human, PE, REAfinity™

01MT14203

Clone REA1435 recognizes mTOR (mechanistic Target of Rapamycin), a serine/threonine protein kinase that is also known as FRAP1 (FK506-binding protein 12-rapamycin-associated protein 1). As a complex, mTOR regulates different cellular processes including cell growth and proliferation, cell motility, cell survival, protein synthesis and transcription. Furthermore, mTOR regulates the activation of insulin receptors and insulin-like growth factor 1 receptors and functions as a target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. mTOR is expressed in sever