MSCA-1 Antibody, anti-human, APC, REAfinity™

01MT07030

Clone REA781 recognizes the human mesenchymal stromal cell antigen-1 (MSCA-1) antigen, a GPI-anchored protein also known as tissue non-specific alkaline phosphatase (TNAP). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271bright population in bone marrow. These CD271brightCD45dim MSCs have a much higher clonogenic capacity compared to the CD271+CD45+ fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential.Additional information: Clone REA781 displays negligible binding to Fc receptors.