Metallothionein Antibody, anti-human, APC, REAfinity™

01MT12283

Clone REA1139 recognizes the human Metallothionein, a cytoplasmatic protein, which has a high content of cysteine and no aromatic amino acids. Metallothionein is able to bind and sequestrate heavy metal ions and is transcriptionally regulated by heavy metals, glucocorticoids, interferon, lymphokines and stress. The isoforms of Metallothionein MT I and MT II have the ability to scavenge free radicals and play a role in carcinogenesis. Overexpression is found in cancers, e.g. different carcinomas and melanoma.Additional information: Clone REA1139 displays negligible binding to Fc receptors.