MACS® GMP CD137-PE

01MT18391

This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4 and CD8 T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. As a costimulatory molecule it is involved in the activation and survival of CD4 or CD8 T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8 T cells, as it is not expressed on resting CD8 T cells and its expression is reliably induced a