Ly-49I Antibody, anti-mouse, APC, REAfinity™

01MT10974

Clone REA1043 recognizes the mouse Ly49I antigen, a single-pass type II C-type lectin-like membrane glycoprotein also known as Ly49 inhibitory receptor I. The Ly49 receptors are encoded by a family of highly polymorphic and polygenic genes within the mouse NK gene complex which includes genes that encode both inhibitory and activating Ly49 receptors. Ly49 receptors recognize MHC-I and MHC-I–like proteins on normal as well as on altered cells. They are described as being expressed on both the developing and mature NK cells. The inhibitory Ly49 receptors are involved in NK cell education, a pro