Ly-49G Antibody, anti-mouse, PE, REAfinity™

01MT10506

Clone REA1022 recognizes the type II transmembrane protein Ly-49G, which is a MHC class I receptor also known as Kira-7. It is expressed on NK, NKT, and T cells. It is reported that the binding of Ly-49G with its ligand leads to inhibition of NK cells, T cells cytotoxicity, cytokine production, and proliferation. The antibody reacts with Ly49G receptor of A/J, BALB/c, C3H, CBA,129, FVB, and SJL mice, but not C57BL/6 mice.Additional information: Clone REA1022 displays negligible binding to Fc receptors.