Lewis Y 抗体，抗人，PE，REAfinity™

01MT00386

Clone REA1487 recognizes the Lewis Y antigen also known as Ley, a carbohydrate determinant expressed at high levels on many human carcinomas, e.g. prostatic adenocarcinomas. The Lewis glycans are a group of substances within the oligosaccharides, which belong to the ABO(H) blood group system and participates in cell–cell recognition. While related to the Lewis blood group system, it is not found on erythrocytes. It is overexpressed on the surface of various human tumors, including breast, colon, lung, and ovarian cancers. Given its strong presence in cancer cells and limited expression in most