Jagged2 Antibody, anti-human, PE-Vio® 770

01MT15610

The MHJ2-523 clone reacts with the Jagged2 protein which is one of the several mammalian Notch ligands. Jagged2 is expressed by various organs and cell types and is involved in regulation of cell differentiation processes, such as lymphocyte development, myogenesis, and neurogenesis. Jagged2 is reported to be essential for the regulation of spermatogenesis. Jagged2 is also expressed on some lymphoma and leukemia cells and various other tumor cells. Jagged2 can be expressed by various antigen-presenting cells and may contribute to APC-directed peripheral T cell differentiation.