IRAK4 Antibody, anti-human, APC, REAfinity™

01MT11733

Clone REA462 recognizes the human interleukin-1 receptor-associated kinase 4 (IRAK4) antigen, regardless of phosphorylation status. IRAK4 is a serine/threonine-protein kinase, which is also known as renal carcinoma antigen NY-REN-64. Interleukin-1 receptor-associated kinases (IRAKs) are key components in the signal transduction pathways utilized by interleukin-1 receptor (IL-1R), interleukin-18 receptor (IL-18R), and toll-like receptors (TLRs). Out of four members in the mammalian IRAK family, IRAK4 is considered to be the “master IRAK”, the only family member indispensable for IL-1R/TLR signa