Integrin α7 Antibody, anti-mouse, Biotin

01MT16819

Clone 3C12 recognizes mouse integrin alpha 7 (Itga7) which belongs to the integrin family of adhesion molecules. Integrins participate in important cell-cell and cell-extracellular matrix interactions in a diverse range of biological processes. Itga7 is a heterodimer consisting of an α and a β subunit and is mainly expressed in skeletal and cardiac muscle. It is a specific cellular receptor for the basement membrane protein laminin-1, as well as for the laminin isoforms-2 and -4 and is involved in differentiation and migration processes during myogenesis. Absence of Itga7 results in muscular d