IL-12 (p40/p70) Antibody, anti-mouse, APC, REAfinity™

01MT02365

Clone REA285 recognizes both, the free and complexed forms (homodimer p80 and heterodimer p70) of the p40 subunit of interleukin-12 (IL-12) as well as of interleukin-23 (IL-23). IL-12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It acts as a growth factor for activated T and natural killer cells, and has a broad array of biological activities. IL-12 has been found to be important for sustaining a sufficient number of memory and eff