IL-12 (p40/p70) Antibody, anti-human, APC, REAfinity™

01MT00845

Clone REA1249 recognizes the Interleukin 12 (IL-12), which is a 70-75 kDa heterodimeric cytokine composed of a 40 kDa heavy chain and a 35 kDa light chain. It is produced mainly by monocytes/macrophages and dendritic cells, primarily in response to stimulation with bacterial or viral antigens. IL-12 displays various effects on both T and NK cells, playing an essential role in the interaction between innate and adaptive immunity. Clone REA1249 reacts with both, the p40 chain and the p70 heterodimer of human IL-12. Additional information: Clone REA1249 displays negligible binding to Fc receptors