I-Aq Antibody, anti-mouse, APC, REAfinity™

01MT04033

Clone REA478 recognizes the mouse I-Aq MHC class II alloantigen. It also recognizes with I-As and I-Av.1. Reactivity with other haplotypes has not been reported. MHC (major histocompatibility complex) class II molecules are a family of molecules normally found on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. Because class II MHC is loaded with extracellular proteins, it is mainly concerned with presentation of extracellular pathogens.Additional information: Clone REA478 displays negligible binding to Fc r