人 XCL1 抗体对
01AB04173
X-C motif chemokine ligand 1 (XCL1), also known as lymphotactin, is a unique member of the C chemokine family, characterized by its single disulfide bond and ability to exist in two conformational states: a monomer (Ltn10) and a dimer (Ltn40). This 114-amino acid protein is primarily secreted by activated CD8+ T cells and natural killer (NK) cells, playing a crucial role in immune responses, particularly in the cross-presentation of antigens by dendritic cells through its exclusive receptor, XCR1. XCL1's involvement extends to various diseases, including rheumatoid arthritis and neuropathic pain, where it contributes to T cell recruitment and inflammatory processes. Its distinct structural features and functional roles make XCL1 a focus of research for therapeutic applications in immunology and pain management.
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技术参数
- 靶点基因名
- XCL1
- 基因别名
- LTN; SCYC1
- 蛋白别名
- X-C motif chemokine ligand 1; XCL1
- UniProt
- P47992
- 物种
- Human
产品详情
- 靶点名称
- XCL1
- 蛋白名称
- X-C motif chemokine ligand 1
- 蛋白别名
- Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1
- 靶点基因名
- XCL1
- 基因别名
- LTN; SCYC1
- UniProt
- P47992
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
X-C motif chemokine ligand 1 (XCL1), also known as lymphotactin, is a unique member of the C chemokine family, characterized by its single disulfide bond and ability to exist in two conformational states: a monomer (Ltn10) and a dimer (Ltn40). This 114-amino acid protein is primarily secreted by activated CD8+ T cells and natural killer (NK) cells, playing a crucial role in immune responses, particularly in the cross-presentation of antigens by dendritic cells through its exclusive receptor, XCR1. XCL1's involvement extends to various diseases, including rheumatoid arthritis and neuropathic pain, where it contributes to T cell recruitment and inflammatory processes. Its distinct structural features and functional roles make XCL1 a focus of research for therapeutic applications in immunology and pain management.