抗人 WDR89 抗体对
01AB02365
WD repeat domain 89 (WDR89) is a member of the WD-repeat protein family, characterized by multiple WD motifs that fold into a β-propeller scaffold to mediate protein-protein interactions. As a non-catalytic platform, WDR89 is predicted to facilitate the assembly of signaling or developmental complexes involved in cell cycle control and organelle biogenesis. Computational models suggest it plays a role in the development of the central nervous system, particularly the corpus callosum and ventricular system. Clinically, WDR89 has been associated with a rare autosomal dominant syndrome characterized by gastrointestinal polyposis, abnormal skin pigmentation, alopecia, and fingernail changes, highlighting its importance in systemic developmental pathways.
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技术参数
- 靶点基因名
- WDR89
- 基因别名
- C14orf150
- 蛋白别名
- WD repeat domain 89; WDR89
- UniProt
- Q96FK6
- 物种
- Human
产品详情
- 靶点名称
- WDR89
- 蛋白名称
- WD repeat domain 89
- 蛋白别名
- WD repeat-containing protein 89
- 靶点基因名
- WDR89
- 基因别名
- C14orf150
- UniProt
- Q96FK6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
WD repeat domain 89 (WDR89) is a member of the WD-repeat protein family, characterized by multiple WD motifs that fold into a β-propeller scaffold to mediate protein-protein interactions. As a non-catalytic platform, WDR89 is predicted to facilitate the assembly of signaling or developmental complexes involved in cell cycle control and organelle biogenesis. Computational models suggest it plays a role in the development of the central nervous system, particularly the corpus callosum and ventricular system. Clinically, WDR89 has been associated with a rare autosomal dominant syndrome characterized by gastrointestinal polyposis, abnormal skin pigmentation, alopecia, and fingernail changes, highlighting its importance in systemic developmental pathways.