人 VWC2 抗体对
01AB01617
Von Willebrand factor C domain containing 2 (VWC2), also referred to as Brorin, is a secreted glycoprotein that functions as a bone morphogenetic protein (BMP) antagonist. By binding to and inhibiting BMP signaling, VWC2 modulates neural development and tissue differentiation. It contains von Willebrand factor C-like domains that facilitate cell adhesion and has been observed to associate with the AMPA receptor complex, suggesting a role in synaptic organization and neuronal function. VWC2 is predominantly expressed in the central nervous system, where it is thought to contribute to neural patterning and the maintenance of neuronal circuits.
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技术参数
- 靶点基因名
- VWC2
- 蛋白别名
- von Willebrand factor C domain containing 2; VWC2
- UniProt
- Q2TAL6
- 物种
- Human
产品详情
- 靶点名称
- VWC2
- 蛋白名称
- von Willebrand factor C domain containing 2
- 蛋白别名
- Brorin; Brain-specific chordin-like protein; von Willebrand factor C domain-containing protein 2
- 靶点基因名
- VWC2
- UniProt
- Q2TAL6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Von Willebrand factor C domain containing 2 (VWC2), also referred to as Brorin, is a secreted glycoprotein that functions as a bone morphogenetic protein (BMP) antagonist. By binding to and inhibiting BMP signaling, VWC2 modulates neural development and tissue differentiation. It contains von Willebrand factor C-like domains that facilitate cell adhesion and has been observed to associate with the AMPA receptor complex, suggesting a role in synaptic organization and neuronal function. VWC2 is predominantly expressed in the central nervous system, where it is thought to contribute to neural patterning and the maintenance of neuronal circuits.