人 UBXN11 抗体对
01AB02915
UBX domain protein 11 (UBXN11) is a cytoplasmic protein characterized by a C-terminal UBX domain, which typically mediates interactions with the valosin-containing protein (VCP) complex. It interacts with Rnd family Rho GTPases and G-protein alpha subunits to regulate actin cytoskeleton organization and Rho signaling pathways. Through these interactions, UBXN11 is implicated in the modulation of cell morphology and cytoskeletal dynamics. Additionally, its ubiquitin-binding capacity suggests a role in proteasome-mediated protein degradation. While specific monogenic diseases are not well-established, expression patterns relate UBXN11 to cellular structural integrity and potentially to tumorigenic processes in specific tissues.
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技术参数
- 靶点基因名
- UBXN11
- 基因别名
- SOC; UBXD5
- 蛋白别名
- UBX domain protein 11; UBXN11
- UniProt
- Q5T124
- 物种
- Human
产品详情
- 靶点名称
- UBXN11
- 蛋白名称
- UBX domain protein 11
- 蛋白别名
- UBX domain-containing protein 11; Colorectal tumor-associated antigen COA-1; Socius; UBX domain-containing protein 5
- 靶点基因名
- UBXN11
- 基因别名
- SOC; UBXD5
- UniProt
- Q5T124
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
UBX domain protein 11 (UBXN11) is a cytoplasmic protein characterized by a C-terminal UBX domain, which typically mediates interactions with the valosin-containing protein (VCP) complex. It interacts with Rnd family Rho GTPases and G-protein alpha subunits to regulate actin cytoskeleton organization and Rho signaling pathways. Through these interactions, UBXN11 is implicated in the modulation of cell morphology and cytoskeletal dynamics. Additionally, its ubiquitin-binding capacity suggests a role in proteasome-mediated protein degradation. While specific monogenic diseases are not well-established, expression patterns relate UBXN11 to cellular structural integrity and potentially to tumorigenic processes in specific tissues.