人 TXLNA 抗体对
01AB00618
Taxilin alpha (TXLNA), also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF), is a protein encoded by the TXLNA gene in humans. It is primarily produced by T cells and certain malignant B cells and plays a crucial role in controlling the growth and proliferation of both normal and cancerous B cells. TXLNA induces B-cell proliferation, inhibits antibody secretion, and expands selected B-cell subgroups. In terms of disease association, increased alpha-taxilin protein expression is linked to the metastatic and invasive potential of renal cell cancer and may be involved in the cell proliferation of hepatocellular carcinoma (HCC). Additionally, TXLNA is implicated in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
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技术参数
- 靶点基因名
- TXLNA
- 基因别名
- TXLN
- 蛋白别名
- taxilin alpha; TXLNA
- UniProt
- P40222
- 物种
- Human
产品详情
- 靶点名称
- TXLNA
- 蛋白名称
- taxilin alpha
- 蛋白别名
- Alpha-taxilin
- 靶点基因名
- TXLNA
- 基因别名
- TXLN
- UniProt
- P40222
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Taxilin alpha (TXLNA), also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF), is a protein encoded by the TXLNA gene in humans. It is primarily produced by T cells and certain malignant B cells and plays a crucial role in controlling the growth and proliferation of both normal and cancerous B cells. TXLNA induces B-cell proliferation, inhibits antibody secretion, and expands selected B-cell subgroups. In terms of disease association, increased alpha-taxilin protein expression is linked to the metastatic and invasive potential of renal cell cancer and may be involved in the cell proliferation of hepatocellular carcinoma (HCC). Additionally, TXLNA is implicated in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.