人 TIM-1 抗体对
01AB04047
Hepatitis A virus cellular receptor 1 (HAVCR1), also known as TIM-1, is a membrane protein that acts as a receptor for the hepatitis A virus (HAV) and several other pathogens, including Ebola and Zika viruses. This protein is characterized by its immunoglobulin-like structure and is involved in various immune responses, particularly in T-helper cell development and regulation of asthma and allergic diseases. Dysregulation or mutations in HAVCR1 can lead to increased susceptibility to viral infections and may influence the severity of diseases such as hepatitis A, where it facilitates viral entry into host cells. Additionally, HAVCR1 has been implicated in kidney injury and repair processes, highlighting its role beyond viral interactions.
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技术参数
- 靶点基因名
- HAVCR1
- 基因别名
- KIM1; TIM1; TIMD1
- 蛋白别名
- hepatitis A virus cellular receptor 1; TIM-1
- UniProt
- Q96D42
- 物种
- Human
产品详情
- 靶点名称
- TIM-1
- 蛋白名称
- hepatitis A virus cellular receptor 1
- 蛋白别名
- Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1; CD antigen CD365
- 靶点基因名
- HAVCR1
- 基因别名
- KIM1; TIM1; TIMD1
- UniProt
- Q96D42
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Hepatitis A virus cellular receptor 1 (HAVCR1), also known as TIM-1, is a membrane protein that acts as a receptor for the hepatitis A virus (HAV) and several other pathogens, including Ebola and Zika viruses. This protein is characterized by its immunoglobulin-like structure and is involved in various immune responses, particularly in T-helper cell development and regulation of asthma and allergic diseases. Dysregulation or mutations in HAVCR1 can lead to increased susceptibility to viral infections and may influence the severity of diseases such as hepatitis A, where it facilitates viral entry into host cells. Additionally, HAVCR1 has been implicated in kidney injury and repair processes, highlighting its role beyond viral interactions.