人 SPON1 抗体对
01AB00416
Spondin 1 (SPON1), also known as F-spondin, is a cell adhesion protein that plays a crucial role in promoting the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. Structurally, it contains 807 amino acids and is composed of six thrombospondin domains, one reelin domain, and one spondin domain. SPON1 is secreted by cells of the floor plate and is involved in axon guidance. Recent studies have also suggested that SPON1 may have therapeutic potential in Alzheimer's disease, as it has been shown to reduce amyloid beta and reverse cognitive impairment and memory dysfunction in a mouse model.
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技术参数
- 靶点基因名
- SPON1
- 基因别名
- KIAA0762; VSGP
- 蛋白别名
- spondin 1; SPON1
- UniProt
- Q9HCB6
- 物种
- Human
产品详情
- 靶点名称
- SPON1
- 蛋白名称
- spondin 1
- 蛋白别名
- Spondin-1; F-spondin; Vascular smooth muscle cell growth-promoting factor
- 靶点基因名
- SPON1
- 基因别名
- KIAA0762; VSGP
- UniProt
- Q9HCB6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Spondin 1 (SPON1), also known as F-spondin, is a cell adhesion protein that plays a crucial role in promoting the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. Structurally, it contains 807 amino acids and is composed of six thrombospondin domains, one reelin domain, and one spondin domain. SPON1 is secreted by cells of the floor plate and is involved in axon guidance. Recent studies have also suggested that SPON1 may have therapeutic potential in Alzheimer's disease, as it has been shown to reduce amyloid beta and reverse cognitive impairment and memory dysfunction in a mouse model.