人 SPATA24 抗体对
01AB01597
Spermatogenesis associated 24 (SPATA24), also known as TIPT2, is a nuclear and cytosolic DNA-binding protein that functions as a transcriptional co-regulator during germ cell differentiation. It exhibits high-affinity DNA binding and works in coordination with geminin (GMNN) and TATA-binding protein (TBP) to activate TATA box-containing promoters. Furthermore, it cooperates with GMNN and TBPL1 to activate TATA-less promoters, such as the NF1 promoter, suggesting a specialized role in regulating cell cycle-linked gene expression during spermatogenesis. Predominantly expressed in the testis and male reproductive tissues, SPATA24 is essential for proper male germ cell development and differentiation.
| 规格 | 起售价 |
|---|---|
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技术参数
- 靶点基因名
- SPATA24
- 蛋白别名
- spermatogenesis associated 24; SPATA24
- UniProt
- Q86W54
- 物种
- Human
产品详情
- 靶点名称
- SPATA24
- 蛋白名称
- spermatogenesis associated 24
- 蛋白别名
- Spermatogenesis-associated protein 24; Testis protein T6441 homolog
- 靶点基因名
- SPATA24
- UniProt
- Q86W54
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Spermatogenesis associated 24 (SPATA24), also known as TIPT2, is a nuclear and cytosolic DNA-binding protein that functions as a transcriptional co-regulator during germ cell differentiation. It exhibits high-affinity DNA binding and works in coordination with geminin (GMNN) and TATA-binding protein (TBP) to activate TATA box-containing promoters. Furthermore, it cooperates with GMNN and TBPL1 to activate TATA-less promoters, such as the NF1 promoter, suggesting a specialized role in regulating cell cycle-linked gene expression during spermatogenesis. Predominantly expressed in the testis and male reproductive tissues, SPATA24 is essential for proper male germ cell development and differentiation.