人 SNAP25 抗体对
01AB00118
SNAP25 is a protein involved in the regulation of neurotransmitter release and synaptic plasticity. Genetic studies have found associations between SNAP25 gene variants and several neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD), autism spectrum disorder, and epilepsy. Altered expression levels or function of SNAP25 may contribute to the pathogenesis of these conditions by disrupting neurotransmission, synaptic vesicle trafficking, and calcium dynamics. In Parkinson's disease specifically, SNAP25 concentration is increased in the cerebrospinal fluid, and this increase correlates with cognitive impairment severity, suggesting a potential role for SNAP25 in the cognitive deficits associated with the disease.
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技术参数
- 靶点基因名
- SNAP25
- 基因别名
- SNAP
- 蛋白别名
- synaptosome associated protein 25; SNAP25
- UniProt
- P60880
- 物种
- Human
产品详情
- 靶点名称
- SNAP25
- 蛋白名称
- synaptosome associated protein 25
- 蛋白别名
- Synaptosomal-associated protein 25; SNAP-25; Super protein; SUP; Synaptosomal-associated 25 kDa protein
- 靶点基因名
- SNAP25
- 基因别名
- SNAP
- UniProt
- P60880
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
SNAP25 is a protein involved in the regulation of neurotransmitter release and synaptic plasticity. Genetic studies have found associations between SNAP25 gene variants and several neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD), autism spectrum disorder, and epilepsy. Altered expression levels or function of SNAP25 may contribute to the pathogenesis of these conditions by disrupting neurotransmission, synaptic vesicle trafficking, and calcium dynamics. In Parkinson's disease specifically, SNAP25 concentration is increased in the cerebrospinal fluid, and this increase correlates with cognitive impairment severity, suggesting a potential role for SNAP25 in the cognitive deficits associated with the disease.