人 SERPINB8 抗体对
01AB00397
Serpin family B member 8 (SERPINB8) is an intracellular serine protease inhibitor that plays a crucial role in regulating protease activity within various physiological processes, particularly in epithelial tissues like the skin. The protein, encoded by a gene located on chromosome 18q21.3, consists of approximately 376 amino acids with a molecular weight of around 42 kDa and features a typical serpin structure with three β-sheets and multiple α-helices. SERPINB8 is involved in inhibiting serine proteases, protecting tissues from protease-mediated damage, and is linked to several skin conditions, including peeling skin syndrome type B and inflammatory skin diseases like psoriasis and eczema. Its function is essential for maintaining tissue integrity and regulating inflammatory responses.
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技术参数
- 靶点基因名
- SERPINB8
- 基因别名
- PI8
- 蛋白别名
- serpin family B member 8; SERPINB8
- UniProt
- P50452
- 物种
- Human
产品详情
- 靶点名称
- SERPINB8
- 蛋白名称
- serpin family B member 8
- 蛋白别名
- Serpin B8; Cytoplasmic antiproteinase 2; CAP-2; CAP2; Peptidase inhibitor 8; PI-8
- 靶点基因名
- SERPINB8
- 基因别名
- PI8
- UniProt
- P50452
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Serpin family B member 8 (SERPINB8) is an intracellular serine protease inhibitor that plays a crucial role in regulating protease activity within various physiological processes, particularly in epithelial tissues like the skin. The protein, encoded by a gene located on chromosome 18q21.3, consists of approximately 376 amino acids with a molecular weight of around 42 kDa and features a typical serpin structure with three β-sheets and multiple α-helices. SERPINB8 is involved in inhibiting serine proteases, protecting tissues from protease-mediated damage, and is linked to several skin conditions, including peeling skin syndrome type B and inflammatory skin diseases like psoriasis and eczema. Its function is essential for maintaining tissue integrity and regulating inflammatory responses.