人 SEMA6C 抗体对
01AB04145
Semaphorin-6C (SEMA6C) is a member of the semaphorin family of proteins, which are primarily known for their roles in axon guidance and neuronal development. SEMA6C is a transmembrane protein that interacts with various receptors, including plexins, to mediate signaling pathways essential for cell communication and migration. Recent studies have highlighted its involvement in cancer biology, where SEMA6C expression is linked to tumor growth and progression. Specifically, silencing SEMA6C in cancer cells leads to growth arrest and increased levels of cell cycle inhibitors, indicating its role in promoting cell proliferation. Furthermore, SEMA6C has been implicated in the activation of signaling pathways involving FAK and YAP, which are critical for cellular survival under stress conditions. Dysregulation of SEMA6C may contribute to various diseases, including certain cancers and neurodevelopmental disorders.
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技术参数
- 靶点基因名
- SEMA6C
- 基因别名
- KIAA1869; SEMAY
- 蛋白别名
- semaphorin 6C; SEMA6C
- UniProt
- Q9H3T2
- 物种
- Human
产品详情
- 靶点名称
- SEMA6C
- 蛋白名称
- semaphorin 6C
- 蛋白别名
- Semaphorin-6C; Semaphorin-Y; Sema Y
- 靶点基因名
- SEMA6C
- 基因别名
- KIAA1869; SEMAY
- UniProt
- Q9H3T2
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Semaphorin-6C (SEMA6C) is a member of the semaphorin family of proteins, which are primarily known for their roles in axon guidance and neuronal development. SEMA6C is a transmembrane protein that interacts with various receptors, including plexins, to mediate signaling pathways essential for cell communication and migration. Recent studies have highlighted its involvement in cancer biology, where SEMA6C expression is linked to tumor growth and progression. Specifically, silencing SEMA6C in cancer cells leads to growth arrest and increased levels of cell cycle inhibitors, indicating its role in promoting cell proliferation. Furthermore, SEMA6C has been implicated in the activation of signaling pathways involving FAK and YAP, which are critical for cellular survival under stress conditions. Dysregulation of SEMA6C may contribute to various diseases, including certain cancers and neurodevelopmental disorders.