抗人 RTL9 抗体对
01AB02027
Retrotransposon Gag like 9 (RTL9) is a human protein-coding gene derived from long terminal repeat (LTR) retrotransposons, belonging to the mammalian apparent LTR retrotransposon (Mar/Mart) family. Although it has lost the capacity for autonomous retrotransposition, RTL9 encodes a large Gag-like protein structurally related to retroviral matrix and capsid proteins. Experimental evidence suggests that RTL9 plays a role in innate immune responses, specifically participating in the degradation of fungal components within the brain. It exhibits tissue-restricted expression with significant enrichment in neural tissues, where it is thought to contribute to specialized host defense mechanisms.
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技术参数
- 靶点基因名
- RTL9
- 基因别名
- KIAA1318; RGAG1
- 蛋白别名
- retrotransposon Gag like 9; RTL9
- UniProt
- Q8NET4
- 物种
- Human
产品详情
- 靶点名称
- RTL9
- 蛋白名称
- retrotransposon Gag like 9
- 蛋白别名
- Retrotransposon Gag-like protein 9; Retrotransposon gag domain-containing protein 1; Tumor antigen BJ-HCC-23
- 靶点基因名
- RTL9
- 基因别名
- KIAA1318; RGAG1
- UniProt
- Q8NET4
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Retrotransposon Gag like 9 (RTL9) is a human protein-coding gene derived from long terminal repeat (LTR) retrotransposons, belonging to the mammalian apparent LTR retrotransposon (Mar/Mart) family. Although it has lost the capacity for autonomous retrotransposition, RTL9 encodes a large Gag-like protein structurally related to retroviral matrix and capsid proteins. Experimental evidence suggests that RTL9 plays a role in innate immune responses, specifically participating in the degradation of fungal components within the brain. It exhibits tissue-restricted expression with significant enrichment in neural tissues, where it is thought to contribute to specialized host defense mechanisms.