
人 RPS6KC1 抗体对
01AB02534
Ribosomal protein S6 kinase C1 (RPS6KC1) is a cytoplasmic serine/threonine protein kinase belonging to the AGC kinase family. It functions in signal transduction and vesicular trafficking by binding to sphingosine kinase and phosphatidylinositol 3-phosphate, thereby participating in sphingosine-1-phosphate-mediated signaling and endosomal phosphoinositide pathways. RPS6KC1 also interacts with the mitochondrial antioxidant enzyme peroxiredoxin-3 (PRDX3), facilitating its recruitment to early endosomes. This interaction suggests a role for RPS6KC1 in coordinating redox regulation with mitochondrial function and endosomal dynamics. Its primary activities include ATP binding and phosphatidylinositol binding, which support its role as a key regulator of intracellular signaling and transport processes.
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技术参数
- 靶点基因名
- RPS6KC1
- 基因别名
- RPK118
- 蛋白别名
- ribosomal protein S6 kinase C1; RPS6KC1
- UniProt
- Q96S38
- 物种
- Human
产品详情
- 靶点名称
- RPS6KC1
- 蛋白名称
- ribosomal protein S6 kinase C1
- 蛋白别名
- Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein
- 靶点基因名
- RPS6KC1
- 基因别名
- RPK118
- UniProt
- Q96S38
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Ribosomal protein S6 kinase C1 (RPS6KC1) is a cytoplasmic serine/threonine protein kinase belonging to the AGC kinase family. It functions in signal transduction and vesicular trafficking by binding to sphingosine kinase and phosphatidylinositol 3-phosphate, thereby participating in sphingosine-1-phosphate-mediated signaling and endosomal phosphoinositide pathways. RPS6KC1 also interacts with the mitochondrial antioxidant enzyme peroxiredoxin-3 (PRDX3), facilitating its recruitment to early endosomes. This interaction suggests a role for RPS6KC1 in coordinating redox regulation with mitochondrial function and endosomal dynamics. Its primary activities include ATP binding and phosphatidylinositol binding, which support its role as a key regulator of intracellular signaling and transport processes.